Alzheimer’s disease
Alzheimer’s disease is a brain disorder named after Alois Alzheimer, the person who first described it.
Symptoms
- Is a progressive and fatal brain disease.
- Alzheimer's destroys brain cells, causing problems with memory, thinking and behavior severe enough to affect work or social life.
- Alzheimer’s gets worse over time, and it is fatal.
- Is the most common form of dementia (the loss of memory) and other intellectual abilities serious enough to interfere with daily life
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Alzheimer's and the brain
As we become old, our ability to think and remember also becomes slow.
But, serious memory loss, confusion and other major changes in the way
our minds work are not a normal part of aging. They may be a sign that
brain cells are failing.
The brain has 100 billion nerve cells (neurons). Each nerve cell
communicates with many others to form networks. Nerve cell networks
have special jobs. Some are involved in thinking, learning and
remembering. Others help us see, hear and smell. Still others tell our
muscles when to move.
To do their work, brain cells operate like tiny factories. They take in
supplies, generate energy, construct equipment and get rid of waste.
Cells also process and store information. Keeping everything running
requires coordination as well as large amounts of fuel and
oxygen.
In Alzheimer’s disease, parts of the cell’s factory stop running well
which affects the other functions too. As damage spreads, cells
lose their ability to do their jobs well. Eventually, they die.
The role of plaques and tangles
Two abnormal structures called plaques and tangles are prime suspects
in damaging and killing nerve cells.
- Plaques build up between nerve cells and tangles are twisted fibers that form inside dying cells. Though most people develop some plaques and tangles as they age, those with Alzheimer’s tend to develop far more. The plaques and tangles begin to form in areas important in learning and memory and then spread to other regions.
Early stage and early onset
Early-stage is the early part of Alzheimer’s disease when problems with
memory, thinking and concentration may begin to appear. The term
early-onset refers to Alzheimer's that occurs in a person under age
65.
Treatment
Has no current cure. But treatments for symptoms, combined with the
right services and support, can make life better for people with
Alzheimer’s.
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